Please use this identifier to cite or link to this item: http://111.93.204.14:8080/xmlui/handle/123456789/695
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dc.contributor.authorBera, Pradip-
dc.contributor.authorBrandao, Paula-
dc.contributor.authorMondal, Gopinath-
dc.contributor.authorJana, Harekrishna-
dc.contributor.authorJana, Abhimanyu-
dc.contributor.authorSantra, Ananyakumari-
dc.contributor.authorBera, Pulakesh-
dc.date.accessioned2022-07-18T10:06:34Z-
dc.date.available2022-07-18T10:06:34Z-
dc.date.issued2017-
dc.identifier.issn0277-5387-
dc.identifier.urihttp://111.93.204.14:8080/xmlui/handle/123456789/695-
dc.description.abstractThe present work report the synthesis, structural characterization and in vitro antibacterial studies of 4-(4- methoxy phenyl)-2-(2-(1-pyridine-2-yl)ethylidene) hydrazinyl)thiazole bromide (HL∙Br) and its cobalt(III) complex, [CoL2]ClO4. HL∙Br crystallizes in a space group Pbca in a nearly planar structure and the crystal structure of complex shows a CoIIIN6 coordination geometry in which each L shows N,N,N-donor binding modes. Solution magnetic susceptibility measurement of [CoL2]ClO4 by modified Evan’s method confirms the low spin diamagnetic nature of the cobalt(III) complex. New compounds were screened for their antibacterial studies against gram positive bacteria including Staphylococcus aureus, Streptococcus fecalis and Bacillus and gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa, Salmonella Typhi, Klebsiella and Proteus vulgaris. Both the compounds show very stronger growth inhibition activity against gram negative bacteria than gram positive bacteria. Present study shows that HL∙Br has maximum antibacterial activity E.coli (25±0.2 mm) and S.typhi (28±0.7 mm) at an MIC of 200 µg/mL and 50 µg/mL respectively, showing greater MIC values than the standard antibiotic ciprofloxacin (8 µg/mL against E.coli and 10 µg/mL against S.typhi).en_US
dc.language.isoenen_US
dc.publisherPolyhedronen_US
dc.subjectThiazoleen_US
dc.subjectHydrazoneen_US
dc.subjectCo(III)complexen_US
dc.subjectCrystallographyen_US
dc.subjectAntibacterial activityen_US
dc.titleSynthesis of a new pyridinyl thiazole ligand with hydrazone moiety and its cobalt(III) complex: X-ray crystallography, in vitro evaluation of antibacterial activityen_US
dc.typeArticleen_US
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